Atomic force microscopy (AFM) has emerged as an indispensable technique for probing the mechanical and structural properties of living cells at nanometre resolution. By employing a sharp probe to ...

AFM is a scanning probe microscopic instrument that consists of a force-sensing microcantilever, a laser source, a piezoelectric scanner and a photodiode detector (Figure 1A). During AFM imaging, the ...

New model extracts stiffness and fluidity from AFM data in minutes, enabling fast, accurate mechanical characterization of living cells at single-cell resolution. (Nanowerk Spotlight) Cells are not ...

Unlike almost every other kind of microscope, atomic-force microscopes (AFMs) don’t use any kind of optical beam to image ...

Thought LeaderProf. Dr. Kristina Kusche-VihrogHead of Department, Institute of PhysiologyUniversity of Lübeck In this interview with News Medical Life Sciences, Prof. Dr. Kristina Kusche-Vihrog, head ...

Macrophages drive key immune processes including inflammation, tissue repair, and tumorigenesis via distinct polarization states whose accurate identification is vital for diagnosis and immunotherapy.

A new method combining AFM with deep learning accurately profiles human macrophage mechanophenotypes. Macrophages drive key immune processes including inflammation, tissue repair and tumorigenesis via ...

Neurological disorders are becoming an increasingly significant societal burden, highlighting the critical need for improved diagnostic and therapeutic approaches. Atomic force microscopy (AFM), known ...

(Nanowerk News) Membrane rafts are nanometer-scale structures rich in cholesterol and sphingolipids, believed to serve as vital platforms for cell signaling, viral entry, and cancer metastasis. Since ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in ACS Applied Nano Materials a new method to precisely measure nuclear elasticity—the stiffness or softness ...