The characteristic pain crises and organ failure seen in sickle cell disease results from the abnormal red blood cells adhesion to the endothelium of small vessels and subsequent blood flow cessation.

The fight against cancer often begins with uncovering hidden players, and a recent study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in ...

Patients with sickle cell disease experience pain and organ failure when their abnormal red blood cells (erythrocytes) block flow through small vessels. This blockage may be initiated by blood cells ...

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal ...

Adhesion molecules are pivotal mediators of cell–cell and cell–matrix interactions that underpin immune surveillance, vascular integrity and tissue homoeostasis. In the cardiovascular system, members ...

Surgical adhesions — internal bands of scar tissue that form between organs or tissues after surgery— can lead to severe complications such as bowel obstructions, chronic pain, and infertility while ...

Q: My doctor said I may have abdominal adhesions after having my appendix removed. What are these? A: Adhesions are basically scar tissue inside your body that may stick (adhere) to body tissue and/or ...