Cell cycle progression is governed by complexes of the cyclin-dependent kinases (CDKs) and their regulatory subunits cyclin and Cks1. CDKs phosphorylate hundreds of substrates, often at multiple sites ...

An organism grows and repairs its body using a form of cell division known as mitosis. To divide, a cell must replicate the chromosomes, which carry the DNA (the instructions needed to build the body) ...

Differences in regulatory T cells (Tregs) in responding and non-responding patients with indolent B-cell or mantle cell lymphoma during treatment with lenalidomide and rituximab ± dexamethasone.

Breakthrough research sheds light on the genetic mutation behind aggressive prostate cancer. Study: CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic ...