Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...

Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also discovered the ...

Hierarchical structure of muscle and activation of thin filaments. In both skeletal and cardiac muscles under a relaxed state, a low intracellular calcium ion concentration is maintained and the ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

THE function of the heart is to propel unoxygenated blood to the lungs and to deliver oxygenated blood to the peripheral tissues in accordance with their metabolic requirements. Since William Harvey's ...

The paper by Parmley et al. in this issue calls attention to the possible therapeutic use of glucagon in view of its possible inotropic and chronotropic effects in man. Such effects have previously ...