Tight junctions (TJs) regulate paracellular permeability, cell polarity and cell mechanics of barrier-forming tissues. This Review explores how TJs adapt their structure and function across tissues, ...
Tight junctions are crucial for maintaining intestinal barrier homeostasis, but how organisms modulate these junctions remain unclear. Here, we show a role for PEAK1 at cell-cell contact sites, where ...
Our skin and mucous membranes are protected by epithelial cells. This 'barrier' tissue performs its function thanks to specialized structures called 'junctions'. They ensure cell cohesion and regulate ...
Top row: The cryo-ET averages of the gap junction channels (left) revealed striking caps (right; purple) on the inside of the cell. Bottom row: The gap junctions (light blue) allow cells to ...
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