Definition: The extracellular matrix is the non-cellular network of proteins and polysaccharides that surrounds cells, gives tissues mechanical structure, and provides biochemical and mechanical ...

Laminins are heterotrimeric glycoproteins that form a fundamental scaffold within the extracellular matrix, particularly in basement membranes. Each laminin molecule comprises α, β and γ chains ...

Aging-related cognitive decline is an early symptom of Alzheimer's disease and other dementias, and on its own can have substantial consequences on an individual's ability to perform important ...

Peptide-based signaling systems continue to occupy a central role in modern biochemical inquiry, particularly in areas concerned with extracellular matrix (ECM) dynamics and structural protein ...