Obtaining prefrontal cortex biopsies during deep brain stimulation (DBS) surgery in living patients does not increase the risk of adverse events or cognitive decline compared to standard DBS ...

Driving a manual car stimulates the prefrontal cortex of the human brain, the region that handles memory, attention, and decision-making.

Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to ...

A traditionally overlooked type of RNA plays an important role in promoting resilience to depression-but only in females. According to a new study led by the Icahn School of Medicine at Mount Sinai, ...

Historically, neuroscientists and evolutionary anthropologists assumed that modern humans' disproportionately large frontal lobes and the explosive growth of our prefrontal cortex millennia ago were ...

Cognitive deficits from dorsolateral prefrontal cortex (dlPFC) dysfunction are common in neuroinflammatory disorders, including long-COVID, schizophrenia and Alzheimer’s disease, where impairments are ...

Prefrontal cortex biopsies taken for research purposes during deep brain stimulation (DBS) procedures appeared to be safe, new research has suggested. Investigators found no significant differences in ...

The results reveal that the human frontal operculum is subdivided into 3 regions, organized on the antero-posterior axis: PCO, located at the level of the precentral gyrus and thus the premotor/motor ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...