aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

The capacity to generate a human model of the kidney via the directed differentiation of human pluripotent stem cells is a remarkable advance. Such three-dimensional multicellular tissues can ...

For the first time, researchers from both Sheba Medical Center and Tel Aviv University have grown human kidney organoids (a synthetic 3D organ culture) from tissue stem cells in the laboratory, ...

Researchers developed tubuloids from adult kidney cells. When exposed to cisplatin, the model replicated key steps in the chronic kidney disease progression, including DNA damage, cellular senescence, ...

A research effort led by scientists from the Keck School of Medicine at the University of Southern California (USC) has led to the development of more mature and complex lab-grown kidney progenitor ...

Ryuji Morizane, MD, PhD, of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new paper published in Signal Transduction and Targeted Therapy, "AAV ...

The difficulty of delivering genes to the kidney has limited the translation of genetic medicines, particularly for the more than 10% of the global population with chronic kidney disease. Here we show ...

Chronic kidney disease (CKD) is a progressive condition that begins with tissue damage and gradually leads to loss of kidney function. The condition, which affects about 10% of the global population, ...