Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Creating a drug that might help treat or cure a health condition in humans is a long, complex process. After developing a candidate drug that shows potential—a process that, in and of itself, can take ...

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...

Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells ...

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead ...

Colorectal liver metastases (CRLM), cancer that has spread from the colon or rectum to the liver, have a deadly reputation. Due to its pervasive spread, typical cancer treatments like chemotherapy and ...