World Series, Shohei Ohtani
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And if you're curious, one pitcher in history has ever had a three-homer game in the regular season. It was Jim Tobin of the 1942 Braves. He went 3 for 4 with three homers and four RBI. He threw a complete game, too. He also allowed five runs (three earned), though.
Really, the only person who would have a valid excuse for fatigue would be Ohtani. He reached base a World Series record nine consecutive times Monday, with two doubles and two homers, and stepped on the mound Tuesday as the first player in World Series to be a starting DH and pitcher in the same game.