Selecting an RNA-seq workflow requires more than matching a kit to a sample type. Choices around ribodepletion, strandedness, and unique molecular identifiers (UMIs) directly influence data quality ...

Inflammatory breast cancer (IBC) is highly aggressive, but extremely difficult to tell apart from other breast cancers.

Scientists have created a new way to map how brain cells connect by assigning each neuron a unique molecular “barcode.” Using this approach, they were able to trace connections among thousands of ...

Evaluation of scCNV inference methods using a clinical small cell lung cancer (SCLC) dataset. (A) Sensitivity and specificity of the four scCNV inference methods applied to primary and relapse SCLC ...

Morgan Hiebert (left) studies drug-resistant tuberculosis within the National Reference Centre for Mycobacteriology (Winnipeg, Manitoba) led by Hafid Soualhine, situated in the National Microbiology ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...

Researchers at The University of Texas MD Anderson Cancer Center and The University of Texas at Austin have identified ...

Bacteria aren’t just mindless microbes. Research by scientists at the Hebrew University of Jerusalem has revealed that single bacterial cells can carry a “memory” of their past environments—passing it ...