To function normally, nearly every cell in the human body relies on G-protein-coupled receptors (GPCRs) to receive and send ...

Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, these molecules also play an important role in normal cellular signaling.

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send ...

Can eating fat be good for us? Some fatty acid molecules actually play a crucial role in maintaining our health and cellular functions. By the early twentieth century, scientists and doctors widely ...

Cornell researchers have uncovered a built-in molecular "gate" that controls the production of the molecule nitric oxide, a crucial signaling molecule throughout biology that in humans helps regulate ...

Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue ...

Cytokines are signaling molecules that coordinate complex immune processes and are frequently dysregulated in disease. While cytokine blockade has become a common therapeutic modality, cytokine ...

Its origin from mitochondrial DNA suggests that it may function as part of a retrograde signaling system, where mitochondria ...

Peptide-based signaling molecules occupy an essential space in biological communication, participating in regulatory networks ...

One of the most important mechanisms is receptor-mediated signaling. A peptide attaches to a specific receptor on the cell surface, which then activates intracellular proteins such as kinases or ...

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in ...

Restoring the lipid molecule erucamide via nanoparticles activates immune cells to slow retinal degeneration and vision loss.