The San Francisco 49ers secured their spot in the divisional round with Sunday night's wild card round win over the Philadelphia Eagles. Now, the No. 6 seed 49ers are preparing for next week's playoff matchup against the No.

The Seattle Seahawks will take on the San Francisco 49ers for the third time this year. Seattle bookended the 2025 regular season with games against San Francisco in Weeks 1 and 18, and now they'll have to face them in the Divisional Round of the playoffs.

Still, the Eagles have played with fire throughout this entire season, and Sunday night was no different. Nick Sirianni's team had a strong offensive start but sputtered down the stretch, allowing a banged-up 49ers team decimated by injuries to hold a 23-19 lead with less than 3:00 minutes remaining in regulation.

The Seahawks at least won’t have to do much studying to prepare for their first home playoff game in five years. San Francisco’s 23-19 win in Philadelphia Sunday afternoon against the Eagles assured that the 49ers will come to Seattle to play the Seahawks in the divisional round next weekend.

NFL playoff odds for Seattle Seahawks vs San Francisco 49ers NFC divisional round game, including point spread, moneyline, over/under for betting.

The San Francisco 49ers will take on the Seattle Seahawks in the divisional round of the NFL playoffs. Here's a look at the early odds.

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Seattle Seahawks offensive coordinator Klint Kubiak and defensive coordinator Aden Durde have both interviewed for head coaching jobs with other teams