GLENDALE -- San Francisco 49ers TE George Kittle will play in Week 18's regular season finale against the Arizona Cardinals.

Joshua Dobbs — starting for the 49ers in the place of injured Brock Purdy — threw for 326 yards, two touchdowns and two ...

Ari_FG Ryland 49, :00. Drive: 5 plays, 39 yards, 00:16. Key Play: Murray 25 pass to Z.Jones. Arizona 20, San Francisco 17. Ari_Dortch 2 pass from Murray (run failed), 8:28. Drive: 6 plays, 49 yards, 3 ...

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

More than a dozen residents in San Francisco were evacuated Saturday following a gas leak, according to the San Francisco ...

The San Francisco Police Department (SFPD) arrested a 29-year-old man after a Saturday night shooting left another man critically injured. San Francisco PD said ...

San Francisco’s Mayor-Elect, Daniel Luries, is participating in a weekend of service just a few days before his inauguration. Christie Smith reports. San Francisco's Mayor-Elect, Daniel Luries, is ...

A billboard campaign along Bay Area freeways is featuring people, as young as one-year-old, who have lost their lives to fentanyl.

Police in San Francisco have made an arrest after a man was fatally shot in the city's Mission District shortly after the ...

Lions vs. 49ers predictions and expert picks for Monday Night Football on December 30. Expect a big night from Jauan Jennings ...

When she later requested video footage from Waymo to report the incident, she said the company declined to share it. Similar ...

The San Francisco Giants’ good-vibes offseason officially ended on Saturday. Corbin Burnes agreed to a six-year, $210 million seal with Arizona.