Can’t Look Up? Think Parinaud Syndrome | Dorsal Midbrain Lesion Light–near dissociation, convergence-retraction nystagmus, eyelid retraction (Collier’s sign), and impaired upgaze point toward Parinaud syndrome. This classic dorsal midbrain (pretectal) lesion is most commonly caused by pineal region tumors, but can also result from multiple sclerosis, hydrocephalus (setting-sun sign), or midbrain stroke. A high-yield clinical and imaging diagnosis—especially for exams and neuro rounds. 👇 Type “P